Methyl Jasmonate - Clinical Results

A newly published paper reports the first clinical results from Methyl Jasmonate:

Eur Rev Med Pharmacol Sci. 2011 Mar;15(3):333-6.

A preliminary study of the local treatment of preneoplastic and malignant skin lesions using methyl jasmonate.

Palmieri B, Iannitti T, Capone S, Flescher E.

Source

Department of General Surgery and Surgical Specialties, University of Modena and Reggio Emilia Medical School, Surgical Clinic, Modena, Italy.

Abstract

BACKGROUND:

Jasmonates are plant stress hormones. These small hydrophobic compounds exhibit anti-cancer activities, in vitro and in vivo, against cancer cells of various histological origins. Moreover, they show a selective activity against transformed cells and affect drug-resistant cells as well.

AIM:

The aim of this study was to evaluate the activity of a powerful jasmonate derivative, that is methyl jasmonate.

MATERIAL AND METHODS:

Methyl jasmonate was applied topically on cancerous and pre-cancerous skin lesions from eight patients.

RESULTS:

Methyl jasmonate did not cause any meaningful local or systemic side effects. Three patients exhibited positive responses. Two patients had complete recovery and one had a recurrence of the lesion three months post treatment.

CONCLUSIONS:

Methyl jasmonate is a potentially promising novel topical treatment for prcancerous and cancerous skin lesions. Methyl jasmonate should be evaluated in a larger series of patients.

This is interesting and encouraging news.

It does lead me to ask the question: are there any readers of the original Grouppe Kurosawa who tried Methyl Jasmonate? The old blog was always short of people reporting back their experiences, yet we do know that lots of people did take Steve Martin's advice to try it.


If you want to help other people, then please report back your experiences - good, bad or indifferent. Please.